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以卵巢切除术制做绝经期后骨质疏松症大鼠模型，应用双能Ｘ线骨密度扫描技术动态观测该模型骨丢失的程度和灌服自拟中药密骨煎的防治作用，结果显示模型组术后８周与对照组比较有异常骨丢失（Ｐ＜０．００１）；中药组骨丢失程度较模型组明显减轻（Ｐ（０．００５）；表明密骨煎对绝经期后骨质疏松症有防治作用。
Ovariectomy in the postmenopausal osteoporosis rat model, the use of dual-energy X-ray absorptiometry technology to dynamically observe the degree of bone loss in this model and self-made traditional Chinese medicine Gugucao prevention and treatment results show that the model Compared with the control group, there was abnormal bone loss at 8 weeks after operation (P <0.001). The degree of bone loss in traditional Chinese medicine group was significantly lower than that of the model group (P <0.005). The results showed that the effect of Miaogu Jian on postmenopausal osteoporosis Disease prevention and treatment.