论文部分内容阅读
最新研究显示生长激素释放激素(GHRH,又称生长释放素)可增加脂质营养不良的HIV感染男性的骨转化标志物。来自于美国哈佛大学医学院的Steven Grinspoon教授及其同事强调指出,骨密度减少与脂质营养不良的HIV患者的躯干和内脏肥胖倾向关联,患者的生长激素亦降低；腹部脂肪越多,骨密度就越低,生长激素水平亦越低。Grinspoon推测躯干脂肪增加是否与这些结果有关；此前研究证实GHRH治疗可减少腹部和内脏脂肪,增加胰岛素样生长因子-1 (IGF-1)。本项研究旨在确定GHRH治疗三个月是否有可能影响骨转化标志物。研究人员随机将31例腹部脂
Recent research shows that growth hormone releasing hormone (GHRH), also known as growth-releasing hormone, increases bone turnover markers in HIV-infected men with lipodystrophy. Professor Steven Grinspoon and colleagues from Harvard Medical School in the United States emphasize that bone mineral density reduction is associated with a tendency toward trunk and visceral obesity in patients with lipid-poor HIV and patients with reduced growth hormone; more abdominal fat, The lower the lower the level of growth hormone. Grinspoon speculates on whether increased trunk fat is associated with these findings; previous studies confirmed that GHRH treatment reduced abdominal and visceral fat and increased insulin-like growth factor-1 (IGF-1). This study was designed to determine if GHRH treatment for three months is likely to affect bone turnover markers. Researchers randomized 31 patients with abdominal fat