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1891年Koch 曾用结核菌素治疗结核病,但未达到预期的疗效,且有某些患者死于“结核菌素休克”.1903年Friedman 又将一种迅速生长的分支杆菌制成菌苗,对结核病进行免疫预防与治疗.由于证实了现代短程化疗的效果,对有无必要再发展结核病的免疫治疗,产生疑问.在1988年举行的抗结核及肺部疾病的国际联合会上,提出短程化疗历时虽短,但短得不够,且花费甚高.尽管患者病灶中的许多结核菌能在1～2周内被消灭,但治疗必须持
Koch used tuberculin to treat tuberculosis in 1891, but did not achieve the desired effect, and some patients died of “tuberculin shock.” In 1903, Friedman transformed a rapidly growing mycobacterium into a vaccine, Immunization prevention and treatment of tuberculosis.Due to the confirmation of the effect of modern short-course chemotherapy and the question of the immunotherapy of the need of further development of tuberculosis, at the International Federation of Anti-TB and Pulmonary Diseases held in 1988, short-course chemotherapy Although the duration is short, but short enough, and costly.Although many of the patient’s lesions in the tuberculosis can be eliminated within 1 to 2 weeks, but the treatment must be held