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细胞外基质和基底膜的破坏是恶性肿瘤浸润和转移的必要过程，尿激酶型纤溶酶原激活物（ｕＰＡ）是一种丝氨酸蛋白酶，在癌细胞周围的细胞间质和基底膜的破坏过程中起重要作用。作者研究了胃癌组织中癌细胞和基质细胞的ｕＰＡ表达，以及ｕＰＡ的酶学活性。选择７１例胃癌病人的
Destruction of extracellular matrix and basement membrane is a necessary process for the invasion and metastasis of malignant tumors. Urokinase-type plasminogen activator (uPA) is a serine protease that destroys the interstitial and basement membranes surrounding cancer cells. The middle plays an important role. The authors studied the expression of uPA in cancer cells and stromal cells in gastric cancer tissues, as well as the enzymatic activity of uPA. 71 patients with gastric cancer