论文部分内容阅读
人们习惯应用血清肌酐常规法监视肾移植后病人的排斥反应,但其浓度受年龄、体形、肌肉发达情况、营养状况和药物等因素的影响,而且在血清肌酐浓度正常时并不能排除肾小球滤过率(GFR)显著减少的可能性。β_2-微球蛋白(β_2М)是一种低分子量的血浆蛋白,可以经肾小球滤过,并被近曲小管重吸收。血清β_2М水平的增加可以反映合成的增加和/或肾小球滤过缺陷;尿β_2М排泄增加可能反映原发性肾小管重吸收缺陷和/或滤过负荷增加。本文测定了37例肾移植后患者和34例健康人
People are accustomed to using routine serum creatinine monitoring of patients after renal transplantation rejection, but its concentration by age, shape, muscle condition, nutritional status and drugs and other factors, and in normal serum creatinine concentration and can not rule out the glomerular The filtration rate (GFR) is significantly reduced. β_2-microglobulin (β_2М) is a low-molecular-weight plasma protein that can be filtered through the glomerulus and reabsorbed by the proximal tubule. An increase in serum β 2 μΜ levels may reflect increased synthesis and / or glomerular filtration defects; increased urinary β 2 M excretion may reflect primary renal tubular reabsorption deficits and / or increased filtration load. This article measured 37 patients after kidney transplantation and 34 healthy people