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脑血管痉挛(cerebral vasospasm,CVS)是指脑动脉在一段时间内的异常收缩状态,目前已知CVS可继发于多种疾病当中,如蛛网膜下腔出血、高血压脑出血、急性颅脑损伤、脑手术后、脑部炎症等。脑血管痉挛是动脉瘤性蛛网膜下腔出血(aneurysmal subarachnoid hemorrhage,SAH)最常见的并发症。严重的脑血管痉挛可造成脑缺血和脑损害,是增加病人死亡和致残最重要的原因。近年来已受到国内外临床医生的更多重视,并且随着分子生物技术的发展,对SAH所致CVS的发病机制有了更多的认识和更新的进展。
Cerebral vasospasm (CVS) refers to abnormal contraction of the cerebral arteries over a period of time. It is known that CVS can be secondary to various diseases such as subarachnoid hemorrhage, hypertensive cerebral hemorrhage, acute brain Injury, brain surgery, brain inflammation and so on. Cerebral vasospasm is the most common complication of aneurysmal subarachnoid hemorrhage (SAH). Severe cerebral vasospasm can cause cerebral ischemia and brain damage, is to increase the patient’s death and disability, the most important reason. In recent years, more and more attention has been paid by clinicians both at home and abroad. With the development of molecular biology technology, more understanding and new progress have been made in the pathogenesis of CVS induced by SAH.