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目的评价预防艾滋病母婴传播(PMTCT)模式预防先天性梅毒的效果。方法采用PMTCT模式对2012—2013年在舟山市妇幼保健院进行孕期保健管理的妊娠合并梅毒孕妇58例为实验组,同期采用常规干预模式管理的妊娠合并梅毒孕妇45例作为对照组,比较两组人群妊娠合并梅毒的诊断、规范治疗及妊娠结局。结果实验组早期发现并诊断的比例明显高于对照组(P<0.05)。实验组规范治疗率为81.03%,高于对照组的62.22%(P<0.05)。实验组和对照组人群不良妊娠结局发生率分别为8.62%和26.67%,两组差异有统计学意义(P<0.05)。结论运用PMTCT模式阻断梅毒母婴传播可提高妊娠合并梅毒感染孕妇早期发现和诊断,促进妊娠梅毒的规范治疗,减少不良妊娠结局的发生率。
Objective To evaluate the effect of PMTCT prevention on congenital syphilis. Methods Fifty-eight pregnant women with pregnancy complicated with syphilis during pregnancy during the period of 2012-2013 were enrolled in this study. PMTCT model was used as the experimental group. 45 pregnant women with syphilis and pregnancy managed by routine intervention mode during the same period were selected as the control group. Pregnancy with syphilis diagnosis of pregnant women, standardized treatment and pregnancy outcomes. Results The proportion of early detection and diagnosis in the experimental group was significantly higher than that in the control group (P <0.05). The experimental group standardized treatment rate was 81.03%, higher than the control group of 62.22% (P <0.05). The incidence of adverse pregnancy outcomes in the experimental and control groups were 8.62% and 26.67%, respectively, with significant difference between the two groups (P <0.05). Conclusion The use of PMTCT to block the transmission of syphilis can improve the early detection and diagnosis of pregnant women with syphilis infection in pregnancy and promote the standard treatment of syphilis in pregnancy and reduce the incidence of adverse pregnancy outcomes.