根尖周病是发生于根尖周围组织的炎症性疾病,多为牙髓病的继发病,一般可通过非手术治疗,即根管治疗治愈,但临床上仍有部分病例仅根管治疗难以治愈,常将久治不愈的根尖周病称为难治性根尖周病(refractory periapical periodontitis)~([1])。对于难治性根尖周病,通常考虑进行根尖周手术~([2])。但传统根尖手术方法创伤较大,且当手术区域接近上颌窦、下颌神经管等 Apical periodontal disease occurs in the periapical tissue inflammatory disease, mostly secondary to dental pulp disease, generally non-surgical treatment, that is, root canal therapy to cure, but there are still some cases of clinical treatment of root canal only difficult Cure, often perpetuated periapical disease called refractory periapical periodontitis ~ ([1]). For refractory periapical disease, usually consider periapical surgery ~ ([2]). But the traditional apical surgery trauma, and when the surgical area close to the maxillary sinus, mandibular neural tube