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近年来,在医学发达的国家成人急性白血病的疗效已有显著提高,治疗的目标不仅是缓解率的提高,缓解时间和生存时间的延长,而是治愈率的提高。虽然治疗方法仍在不断改进、变化,但经过多年来的临床实践和比较,对某些治疗方法已作出一些比较肯定的结论,有些治疗方法正成为广泛采用的标准方法。现将一些重要的治疗进展作一概述,以供改进我们今后工作参考。急性淋巴细胞白血病(急淋)的治疗缓解诱导基本的诱导化疗方案仍是长春新碱(VCR)加强的松(Pred)的VP方案。为了提高缓解率和延长缓解时间,在此方案中还必须加用一些适当的细胞毒药物。当前国外
In recent years, the curative effect of adult acute leukemia has been significantly improved in medically advanced countries. The goal of treatment is not only the improvement of remission rate, the extension of remission time and survival time, but also the improvement of cure rate. Although the treatment methods are still improving and changing, after some years of clinical practice and comparison, some relatively positive conclusions have been made for certain treatment methods. Some treatment methods are becoming widely used standard methods. A summary of some important treatment developments is now provided for improvement of our future work. The treatment of acute lymphoblastic leukemia (emergency leukemia) remission induction of the basic induction chemotherapy regimen is still a vincristine (VCR) boosted Pred VP regimen. In order to increase the remission rate and extend the remission time, some appropriate cytotoxic drugs must also be added in this program. Currently abroad