在未来持续发展和不可预测的市场环境中，灵敏制造成为保持企业竞争地位与生存发展的一个重要战略。阐述了灵敏制造的特征、内涵，并基于对中国国情的认识，从技术、组织与人三个方面较为详尽地分析了灵敏制造企业的建立原则及关键因素，包括经营过程重构、仿真、优化的方法和工具，扁平化柔性组织体系结构以及人因原理等。提出了解合理的灵敏制造企业设计模型—递阶式模型，为２１世纪灵敏制造企业的建立提供了方法与支持。 In the future sustainable development and unpredictable market environment, sensitive manufacturing has become an important strategy to maintain the competitive position and survival and development of enterprises. The characteristics and connotation of agile manufacturing are expounded. Based on the understanding of China’s national conditions, the establishment principle and key factors of agile manufacturing enterprise are analyzed in detail from the aspects of technology, organization and people, including the reconstruction, simulation and optimization of business processes Methods and tools, flattened flexible tissue architecture and human factors. Proposed to understand the rational design of sensitive manufacturing enterprises model - hierarchical model for the 21st century sensitive manufacturing enterprises to establish the method and support.