准分子激光在20世纪80年代首次用于治疗动脉粥样硬化性血管性疾病,最初仅仅是用于治疗动脉粥样硬化造成的严重肢端缺血[1]。基于激光可以被粥样硬化组织吸收这一特性,产生了激光可以用于治疗冠状动脉和外周血管闭塞病变的理论[2]。在冠状动脉支架诞生之前,对存在狭窄的冠状动脉进行单纯球囊扩张,术后血管的再狭窄甚至闭塞风险仍然较高,而通过激光治疗对斑块进行消融则在当时作为治疗再狭窄或闭塞的一种方法[3]。尽管早年发表的大型临床 Excimer lasers were first used to treat atherosclerotic vascular disease in the 1980’s and were initially only used to treat severe ischemia caused by atherosclerosis [1]. Based on the fact that the laser can be absorbed by atherosclerotic tissue, a theory has emerged that laser can be used to treat coronary and peripheral vascular occlusions [2]. Prior to the birth of a coronary stent, a simple balloon dilatation of a stenosed coronary artery was followed by a still higher risk of restenosis or occlusion of the vessel postoperatively, and ablation of the plaque by laser treatment was then used as a treatment for restenosis or occlusion A method [3]. Despite the large clinical published in early years