临床上早期准确地检出血栓并加以治疗,对于降低血栓并发症的发生率非常重要。采用特异性配体(包括抗体、受体蛋白等)与白蛋白或脂质体连接形成靶向超声造影剂可能是一种很有前途的导向诊断和治疗方法。制备一种能与血栓靶向黏附的超声微泡以及寻找一种适当强度的超声能量来有效诱导增强超声空化作用是达到靶向诊断与助溶治疗的条件。 Clinically accurate and early detection of thrombosis and treatment, for reducing the incidence of thrombotic complications is very important. The use of specific ligands (including antibodies, receptor proteins, etc.) in conjunction with albumin or liposomes to form targeted ultrasound contrast agents may be a promising method for targeted diagnosis and treatment. It is necessary to prepare an ultrasound microbubble that can be targeted with thrombus and to find a proper intensity of ultrasound energy to effectively induce enhanced cavitation.