论文部分内容阅读
目的 观察研究鼻咽癌微血管异常的特征。方法 应用接触式显微内窥镜配合特别装配的数字视频图像系统 ,对活体鼻咽癌病灶及癌旁粘膜表面微血管形态进行观察研究。结果 绝大多数鼻咽癌病灶表面存在具特征性的微血管异常 ,即微血管增生、曲张、迂回扭曲、管径粗细不均、浅表脆弱、易出血。通过对 12 6例鼻咽癌病人及 1154例其它鼻咽病变和正常对照组的检查结果分析 ,将微血管异常程度分为 4级 ,鼻咽癌病灶微血管异常 3级者为 85% ,2级为 12 % ,1级为 3% ;鼻咽炎病人 3级为 0 ,2级为 8% ,1级为 82 % ,0级为 10 % ;正常对照者 1级 4 2 % ,0级 58%。鼻咽囊肿及鼻咽血管纤维瘤等病例也有不同程度的微血管扩张或曲张 ,但不如鼻咽癌典型。结论 微血管增生异常是鼻咽癌具有特征性的一项病理与临床表现 ,可作为显微内窥镜早期诊断鼻咽癌的观察指标之一。
Objective To observe the characteristics of nasopharyngeal microvascular abnormalities. Methods Using the contact micro-endoscope with specially assembled digital video image system, we observed the microvascular morphology on the surface of nasopharyngeal carcinoma and adjacent mucosa. Results Most of the lesions on the surface of nasopharyngeal carcinoma had characteristic microvascular abnormalities, namely microvascular hyperplasia, varicose veins, tortuous twists and turns, uneven diameter and superficial thickness, superficial weakness and easy bleeding. By analyzing the examination results of 126 cases of nasopharyngeal carcinoma and 1154 cases of other nasopharyngeal lesions and normal control group, the degree of microvascular abnormality was divided into 4 grades, 85% of NPC grade 3 microvascular abnormality, 2 grades of 12%, grade 1 was 3%; grade 3 was 0 in patients with nasopharyngitis, grade 2 was 8%, grade 1 was 82%, grade 0 was 10%, grade 1 was 42%, grade 0 58%. Nasopharyngeal cyst and nasopharyngeal angiofibroma and other cases also have varying degrees of microvascular dilation or varicose, but not as good as the typical nasopharyngeal carcinoma. Conclusions Microvascular dysplasia is a characteristic pathological and clinical manifestation of nasopharyngeal carcinoma, which can be used as one of the observation indicators for early diagnosis of nasopharyngeal carcinoma by micro-endoscopy.