阜康阿魏(Ferula fukanensis)根的80%甲醇提取物可抑制脂多糖(LPS)诱导鼠巨噬细胞样细胞系中NO产生,本次从中分离得到4个新的倍半萜香豆素衍生物(1～3、5)。阜康阿魏干燥根(5.9kg)用80%甲醇提取,减压回收溶剂。提取物(44.8g)混悬于水中,依次用氯仿和乙酸乙酯提取。提取液减压回 An 80% methanol extract from the root of Ferula fukanensis inhibited NO production in murine macrophage-like cell lines induced by lipopolysaccharide (LPS), and four new sesquiterpenoids derived from coumarin were isolated from this time. (1 to 3, 5). Fructus Efficata dry root (5.9 kg) was extracted with 80% methanol, and the solvent was recovered under reduced pressure. The extract (44.8 g) was suspended in water and extracted sequentially with chloroform and ethyl acetate. Decompression of the extract