Mott等最近报道,环丙氟哌酸与华法令之间可能存在相互作用,其结果是使凝血酶原时间(PT)延长。本文报道1例患者接受华法令剂量时口服环丙氟哌酸后导致PT延长及出血。病例报告患者女性,74岁,系人工心脏瓣膜置换及严重扩张型心肌病。因不适、头晕及大量便血1d入院。曾用过地高辛、螺 Mott et al recently reported that there may be an interaction between ciprofloxacin and warfarin resulting in an increase in prothrombin time (PT). This article reports the oral administration of ciprofloxacin in one patient receiving warfarin dose resulting in PT prolongation and bleeding. Case report Female patient, 74 years old, Department of Cardiac Valve Replacement and Severe Dilated Cardiomyopathy. Due to discomfort, dizziness and a large number of blood in the stool 1d admission. Used digoxin, snail