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对苄氧基苯甲酸乙酯与二甲亚砜在氢化钠作用下反应生成(4′-苄氧基)-苯甲酰基-二甲亚砜,该亚砜在乙酸酐作用下发生Pummerer重排反应得到1-乙酰氧基-1-甲硫基-(4′-苄氧基)-苯乙酮,在对甲苯磺酸的作用下生成1,1-二甲硫基-(4′-苄氧基)-苯乙酮.产物结构经过红外光谱、核磁共振光谱得到了证实.
The reaction of ethyl benzyloxybenzoate with dimethylsulfoxide under the action of sodium hydride gives (4’-benzyloxy) -benzoyl-dimethylsulfoxide, which undergoes Pummerer rearrangement under the action of acetic anhydride The reaction gives 1-acetoxy-1-methylthio- (4’-benzyloxy) -acetophenone, and 1,1-dimethylthio- (4’-benzyl Oxy) -acetophenone.The structure of the product was confirmed by infrared spectroscopy and nuclear magnetic resonance spectroscopy.