慢性肾脏病(CKD)的发生率呈逐年上升趋势,根据美国肾病数据系统(USRDS)资料,近年来终末期肾病(ESRD)患者的发生率已增长了1倍[1]。心血管疾病(CVD)是CKD患者的主要并发症及其死亡原因,其病死率约占ESRD患者的50%,是普通人群的10～20倍[1,2]。为减少CKD的心血管事件,降低ESRD患 The incidence of chronic kidney disease (CKD) has been increasing year by year. According to the US Data System for Renal Disease (USRDS), the incidence of end-stage renal disease (ESRD) has doubled in recent years [1]. Cardiovascular disease (CVD) is a major complication and cause of death in CKD patients, with a mortality rate that accounts for about 50% of ESRD patients and is 10-20 times more common in the general population [1,2]. To reduce cardiovascular events in CKD, reduce ESRD