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合成了1种苄基三苯基季鏻盐——氯化苄基三苯基季鏻盐([BzTPP]+Cl-);利用元素分析、红外光谱、电子喷雾质谱和X射线单晶衍射对其进行了组成分析和结构表征;采用二倍稀释法测定了其抗菌活性,并与季鏻盐[BzTPP]2[CoCl4]和[BzTPP]2[MnCl4]进行了对比.结果表明,合成的季鏻盐[BzTPP]+Cl-属于正交晶系,Pbca空间群,晶胞参数为:a=1.388 0(1)nm,b=1.717 0(2)nm,c=1.817 5(2)nm,α=β=γ=90°,V=4.131 3(7)nm3,Z=8,Dc=1.191g/cm3,GOOF=1.002,R1=0.038 4,wR2=0.113 6.该季鏻盐由Cl-离子和[BzTPP]+阳离子组成,阴、阳离子之间存在C-H…Cl氢键.与此同时,三种季鏻盐对大肠杆菌、金葡萄球菌及沙门氏菌均具有较好的抗菌活性.
A kind of benzyltriphenylphosphonium quaternary phosphonium salt ([BzTPP] + Cl-) was synthesized. One kind of benzyltriphenylphosphonium salt ([BzTPP] + Cl-) was synthesized by elemental analysis, infrared spectrum, electron spray mass spectrometry and X-ray diffraction Their antibacterial activities were determined by double dilution method and compared with quaternary phosphonium salts [BzTPP] 2 [CoCl4] and [BzTPP] 2 [MnCl4] .The results showed that the synthesis season The phosphonium salt [BzTPP] + Cl- belongs to the orthorhombic and Pbca space group with unit cell parameters of a = 1.388 0 (1) nm, b = 1.717 0 (2) nm and c = 1.817 5 α = β = γ = 90 °, V = 4.131 3 (7) nm3, Z = 8, Dc = 1.191g / cm3, GOOF = 1.002, R1 = 0.0384, wR2 = 0.113 6. The quaternary phosphonium salt is composed of Cl- Ions and [BzTPP] + cation, CH ... Cl hydrogen bonds exist between anion and cation, meanwhile the three quaternary phosphonium salts have good antibacterial activity against Escherichia coli, Staphylococcus aureus and Salmonella.