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目的探讨基层医院临床药师在抗菌药物专项整治活动中的作用及效果。方法临床药师发挥自身专业特长，积极参与抗菌药物临床应用的专项整治活动。对照分析专项整治前后抗菌药物的使用情况。结果专项整治后，抗菌药物的使用率显著降低（P<0.05），达到了控制目标。结论临床药师充分发挥自身优势，可有效促进基层医院抗菌药物的临床合理使用。“,” Objective: To explore the action and effectiveness of clinical pharmacists’ participating in the activities of antibiotics special rectification in a primary hospital.Methods:Clinical pharmacists gave ful play to their own advantages to participate in the activities of antibiotics special rectification. The usage of antibiotics before and after special rectification were controled and analyzed. Results The utilization rate of antibacterial drugs lowed significantly after special rectification(al P<0.05), and reaching the control aim. Conclusion Clinical pharmacists who giving ful play to their own advantages can improve obviously the rational usage of antibacterial drugs for primary hospital in clinic.