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以大剂量大肠杆菌内毒素粗制品注入狗静脉内。造成内毒素休克动物模型,在输液前与注入内毒素后10小时。分别从犬股动脉取血,进行了14项指标的测定,以了解不同药物的疗效。 (1)对凝象的影响:血小板减少率(％),山莨菪碱组46.8±2.4、蟾酥组43.4±5.0、蟾山合液组37.6±2.5、纤维蛋白原减
A large dose of E. coli endotoxin crude was injected into the dog’s vein. An animal model of endotoxin shock was created before infusion with 10 hours after infusing endotoxin. Blood was taken from the femoral femoral artery and 14 indicators were measured to understand the efficacy of different drugs. (1) Effect on coagulation: Thrombocytopenia rate (%), anisodamine group 46.8±2.4, wolfberry group 43.4±5.0, Qishan complex group 37.6±2.5, fibrinogen reduction