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新近研究发现:组织胆固醇快、慢代谢池的大小,和血浆高密度脂蛋白胆固醇(以下简称HDL-C)含量间呈明显负相关。动脉组织内可交换的胆固醇属胆固醇的慢代谢池,就是说,血浆HDL-C含量越高,动脉组织胆固醇含量就会越低。细胞培养实验证明:HDL能抑制细胞摄取、分解和蓄积低密度脂蛋白-胆固醇(以下简称LDL-C),还能促进已蓄积于细胞中的胆固醇的排除。大量流行病学调查表明,血浆HDL水平和冠心病发病率之间,以及它和冠心病某些危险因子之间,都存在明显负相关。我国正常人血清
Recent studies have found: tissue cholesterol fast, slow metabolic pool size, and plasma high-density lipoprotein cholesterol (hereinafter referred to as HDL-C) was significantly negatively correlated. Arterial tissue exchangeable cholesterol is a slow metabolism of cholesterol pool, that is, the higher the content of plasma HDL-C, the arterial tissue cholesterol content will be lower. Cell culture experiments show that: HDL can inhibit cellular uptake, decomposition and accumulation of low-density lipoprotein-cholesterol (hereinafter referred to as LDL-C), but also to promote the accumulation of cholesterol in cells has been excluded. A large number of epidemiological studies have shown that plasma HDL levels and the incidence of coronary heart disease, as well as between it and some of the risk factors of coronary heart disease, there is a clear negative correlation. China’s normal serum