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自1995年2月～1999年5月,我院用足叶乙甙(VP16)、吡喃阿霉素(THP)、顺铂(DDP)组成的EAP方案治疗广泛期小细胞未分化癌28例,观察疗效及毒副反应,现报告如下:1 资料与方法1.1 一般资料:28例中男20例,女8例,年龄40～68岁,平均年龄57岁。全部经病理检查证实,并有影像学检查(CT、X线胸片、B超)临床分期为广泛期,卡氏评分≥60分,肾功能正常。28例中,初治18例,复治10例。1.2 治疗方法:EAP方案为:吡喃阿霉素40mg/m~2静注第1天。第2天～第6天,顺铂80mg/m~2静注第1天(同时全身水
From February 1995 to May 1999, 28 patients with extensive undifferentiated small cell carcinoma were treated with EAP regimen consisting of VP16, TP, and cisplatin (DDP). , Observe the curative effect and side effects, the report is as follows: 1 Materials and Methods 1.1 General Information: 28 cases of 20 males and 8 females, aged 40 to 68 years, mean age 57 years. All confirmed by pathological examination, and imaging (CT, X-ray, B ultrasound) clinical stage is an extensive period, Karp score ≥ 60 points, normal renal function. Of the 28 cases, 18 were initially treated and 10 were retreated. 1.2 treatment: EAP program: pirarubicin 40mg/m~2 intravenous injection on the first day. From the second day to the sixth day, Cisplatin 80 mg/m~2 intravenous injection on the first day (while the body water