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目的探讨广东省汕头地区贲门癌家族易感性的相关因素。方法收集我院１９９０年１月至１９９７年１２月手术切除贲门癌５６４例，对有家族性肿瘤史的５０例贲门癌患者及其亲属患癌者进行调查分析。结果贲门癌的发病存在家族遗传易感性，有家族癌史的患者占８．９％，平均发病年龄５６．５岁。结论贲门癌家族易感性可能与遗传因素、环境因素和家族免疫功能缺陷有关，应予足够重视。
Objective To investigate the related factors of the susceptibility of the cardiac cancer family in Shantou area, Guangdong province. Methods We collected 564 cases of cardiac cancer from January 1990 to December 1997 in our hospital. We investigated 50 cases of cardiac cancer patients and their relatives who had a family history of cancer. Results There was family genetic susceptibility to the onset of cardiac cancer, with 8.9% of patients with a family history of cancer and an average age of 56.5 years. Conclusion The susceptibility of cardiac cancer family may be related to genetic factors, environmental factors and family immune function defects, and should be given enough attention.