根据国家药品监督管理局颁布的新药审批办法的规定 ,对门冬氨酸钾镁氯化钠注射液的溶血性、全身过敏性、血管刺激性进行试验研究。试验结果表明 ,未见门冬氨酸钾镁氯化钠注射液在体外对红细胞有溶血作用 ;对豚鼠经静脉给药 ,未见有过敏性反应 ;从家兔耳缘静脉点滴 ,上下午各一次 ,连续 7d ,光镜下观察 ,未见血管内皮细胞脱落 ,无血栓形成 ,也未见其它异常 According to the regulations of the approval of new drugs promulgated by the State Drug Administration, the hemolytic, systemic allergies and vascular irritation of potassium magnesium magnesium chloride aspartate injection were studied. The results showed that no potassium magnesium magnesium aspartate injection in vitro hemolytic hemolysis of red blood cells; intravenous administration of guinea pigs, no allergic reactions; from the rabbit ear vein drip, the morning and afternoon Once, for 7 days, observed under light microscope, there was no shedding of vascular endothelial cells, no thrombosis and no other abnormalities