论文部分内容阅读
目的:评价阿奇霉素与红霉素联合治疗小儿支原体肺炎的临床疗效。方法:将138例小儿支原体肺炎患者,随机分为治疗组和对照组,每组69例。治疗组:采用乳糖酸红霉素30mg/(kg.d)加入500mL等渗葡萄糖注射液中,静滴7d,同时口服阿奇霉素10mg/(kg.d),服3d停4d为1疗程;对照组:单用阿奇霉素10mg/(kg.d),1次/d,静滴5d停2d为1疗程,无效则改为乳糖酸红霉素静滴,治疗时间均为2～3疗程,比较两组的临床疗效。结果:对照组总有效率为79.71%,治疗组总有效率为95.65%,两组疗效比较,治疗组明显高于对照组,差异有统计学意义(P<0.05);临床症状和体征消退时间比较,差异有统计学意义(P<0.05);其不良反应少且症状轻微,无肺外并发症发生。结论:阿奇霉素联合红霉素治疗小儿支原体肺炎的临床疗效优于单用阿奇霉素。
Objective: To evaluate the clinical efficacy of azithromycin and erythromycin in the treatment of children with mycoplasma pneumonia. Methods: 138 cases of children with mycoplasma pneumonia were randomly divided into treatment group and control group, 69 cases in each group. Treatment group: erythromycin lactobionate 30mg / (kg.d) was added to 500mL isotonic glucose injection, intravenous infusion of 7d, while oral azithromycin 10mg / (kg.d), taking 3d stop 4d for a course of treatment; control group : Azithromycin alone 10mg / (kg.d), 1 / d, intravenous drip 5d stop 2d for a course of treatment, the effect is changed to erythromycin lactobionate intravenously, the treatment time are 2 to 3 courses of treatment, compared two groups The clinical efficacy. Results: The total effective rate of the control group was 79.71%, the total effective rate of the treatment group was 95.65%, the treatment group was significantly higher than the control group, the difference was statistically significant (P <0.05); clinical symptoms and signs of subsided time Compared with the control group, the difference was statistically significant (P <0.05). The adverse reactions were mild with mild symptoms and no extra-pulmonary complications occurred. Conclusion: Azithromycin combined with erythromycin in children with mycoplasma pneumonia is better than the single azithromycin.