威尔逊氏病首由神经病学医生威尔逊氏所描述,是铜代谢障碍的一种疾病,其特点为铜的含量过多和自体隐性遗传,神经性障碍和 Kayser-Fleischer 环曾被强调为应有的征象。但也有表现为慢性活动性肝炎或肝硬化的患者。作者报告二个家族二代人在24例的同型胞子的同胞儿中有7例为威尔逊氏病,这些病人均无神经及眼部表现,故使人怀疑本病并不是肝脏疾患的罕见原因。甲家族的头一个病例表现为慢性活动性肝炎,第二例是慢性肝病变,1例 Wilson’s disease, first described by Wilson’s neurologist Dr. Wilson, is a disorder of copper metabolism characterized by excess copper and autosomal recessive inheritance, neurological disorders, and Kayser-Fleischer rings that have been emphasized as being Signs. But there are also patients with chronic active hepatitis or cirrhosis. The authors report that two of the second and second generation family members had Wilson’s disease in their siblings of the 24 homomorphic spores. None of these patients had neurological and ocular manifestations, so it is suspected that this disease is not a rare cause of liver disease. The first case of familial manifestations of chronic active hepatitis, the second case of chronic liver disease, 1 case