Eaton-Lambert 综合征(ELS)其主要临床表现为无力,易疲劳和反射低下。电生理学研究证实在刺激频率加快或短暂的等长运动,呈现一种递增的复合运动动作电位(CMAP),并通过此种改变以明确其诊断。此综合征似乎涉及IgG 自身抗体,这种抗体干扰神经肌肉接头突触前末端的钙通道。 Eaton-Lambert syndrome (ELS) its main clinical manifestations of weakness, fatigue and low reflection. Electrophysiological studies confirm an accelerating or transiently isometric motility at a stimulus frequency, presenting an increasing level of compound motor action potentials (CMAPs) and making the diagnosis clear by such changes. This syndrome appears to involve IgG autoantibodies that interfere with the calcium channel at the presynaptic terminal of the neuromuscular junction.