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目的:总结布地奈德和特布他林联合雾化吸入治疗小儿哮喘的临床疗效,以提高治疗质量。方法:收治小儿哮喘患儿92例,随机分成对照组和观察组各46例,对照组按支气管哮喘常规治疗,观察组在此基础上,加布地奈德和特布他林联合雾化吸入治疗,2次/日,雾化吸入,15～20分钟/次。结果:对照组显效24例,显效率52.2%,有效9例,有效率19.6%,无效13例,总有效率71.7%;观察组显效39例,显效率84.8%,有效5例,有效率10.9%,无效2例,总有效率95.7%,两组比较两组比较差异有统计学意义(P<0.05)。两组患者哮鸣音、啰音、咳嗽、喘息、呼吸困难改善时间比较差异有显著性(P<0.05),住院时间比较也差异有显著性(P<0.05)。结论:布地奈德和特布他林联合雾化吸入治疗小儿哮喘临床改善时间迅速,临床疗效好。
OBJECTIVE: To summarize the clinical efficacy of budesonide and terbutaline combined with inhalation for the treatment of pediatric asthma, in order to improve the quality of treatment. Methods: 92 children with pediatric asthma were randomly divided into control group and observation group, 46 cases in each group. Patients in the control group were treated routinely with bronchial asthma. On the basis of this, the combination of budesonide and terbutaline in combination with nebulized inhalation , 2 times / day, aerosol inhalation, 15 to 20 minutes / time. Results: In the control group, 24 cases were markedly effective, effective rate was 52.2%, effective rate was 9.6%, effective rate was 19.6%, ineffective in 13 cases and total effective rate was 71.7%. In the observation group, 39 cases were markedly effective, effective rate was 84.8%, effective rate was 10.9 %, 2 cases were ineffective and the total effective rate was 95.7%. There was significant difference between the two groups (P <0.05). There were significant differences in improvement time of wheeze, aura, cough, wheeze and dyspnea between the two groups (P <0.05) and hospital stay (P <0.05). Conclusion: Budesonide and terbutaline combined with nebulized inhalation in the treatment of pediatric asthma clinical improvement time is rapid, clinical curative effect is good.