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患者男,65岁,因膀胱癌术后化疗于2011年10月9日入院。患者于入院前被确诊为膀胱非浸润性低级别乳头状尿路上皮癌,行经尿道膀胱肿瘤绿激光电切术。既往身体健康,无药物过敏史。入院体格检查未见明显阳性体征,生命体征平稳,体温36.5℃,血压130/80mmHg,心率73次/min,脉搏73次/min,呼吸20次/min。化疗方案为表柔比星50mg加入0.9%氯化钠注射液50mL经乳胶导尿管灌注入膀胱,保留30min。灌注约10min后,患者感觉膀胱有灼热感,出现手足发痒,面部及四肢发红,心率100次/min,血压145/87mmHg;灌注20min后,上述症状加
Male patient, age 65, was admitted to hospital on October 9, 2011 due to postoperative chemotherapy for bladder cancer. Patients were diagnosed as low-grade bladder non-invasive papillary urothelial carcinoma before admission and underwent transurethral resection of the bladder tumor by green laser. Past health, no history of drug allergy. Admission physical examination showed no significant positive signs, stable vital signs, body temperature 36.5 ℃, blood pressure 130 / 80mmHg, heart rate 73 beats / min, pulse 73 beats / min, breathing 20 beats / min. Chemotherapy for epirubicin 50mg 0.9% sodium chloride injection by 50mL latex catheter into the bladder, reserved for 30min. After about 10 minutes of perfusion, the patient felt burning sensation of the bladder, itching of hands and feet, redness of face and limbs, heart rate 100 beats / min, blood pressure 145/87 mmHg;