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目的：比较替硝唑和甲硝唑治疗滴虫性阴道炎的疗效。方法：６０例滴虫性阴道炎病人，随机单盲分为２组。替硝唑组３０例，年龄３３±ｓ５ａ（２２～５１ａ），用替硝唑治疗，首日顿服２．０ｇ，ｄ２，ｄ３各顿服１．０ｇ，疗程３ｄ。甲硝唑组３０例，年龄３６±７ａ（２０～５２ａ），用甲硝唑０．２ｇ，ｐｏ，ｔｉｄ，疗程７ｄ。结果：替硝唑组和甲硝唑组总有效率分别为８７％和８０％，２组疗效比较无显著差异（Ｐ＞０．０５），但不良反应发生率分别为２３％和７０％，有显著性差异（Ｐ＜０．０１）。结论：替硝唑治疗滴虫性阴道炎疗程短，不良反应小。
Objective: To compare the efficacy of tinidazole and metronidazole in the treatment of trichomonas vaginitis. Methods: Sixty patients with trichomonas vaginitis were randomized into two groups. Tinidazole group, 30 cases, age 33 ± s5a (22 ~ 51a), with tinidazole treatment, the first day of service 2.0g, d2, d3 each Dayton clothing 1.0g, course of treatment 3d. Metronidazole 30 patients, age 36 ± 7a (20 ~ 52a), with metronidazole 0.2g, po, tid, treatment 7d. Results: The total effective rates of tinidazole group and metronidazole group were 87% and 80%, respectively. There was no significant difference between the two groups (P> 0.05), but the incidence of adverse reactions were 23% and 70%, respectively There was significant difference (P <0.01). Conclusion: Tinidazole treatment of trichomonas vaginitis short course of treatment, adverse reactions.