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本文以胶质银技术对小儿再障及正常儿童骨髓细胞增殖活性进行了探讨。其中包括正常骨髓8例,急性再障7例,慢性再障12例。结果显示急、慢性再障骨髓细胞AgNOR均值显著低于正常对照组。急性再障内依次以巨核细胞、早中幼红、早中幼粒细胞AgNOR均值下降最为突出(P<0.001~0.01)。急慢性再障之间AgNOR均值也有显著性差异(P<0.01)。作者认为AgNOR技术对于小儿再障的诊断、疗效判定及骨髓细胞增生障碍机理的探讨均有一定实用价值。
In this paper, colloidal silver technology in children with aplastic anemia and normal children’s bone marrow cell proliferation activity were discussed. Including 8 cases of normal bone marrow, acute aplastic anemia in 7 cases, 12 cases of chronic aplastic anemia. The results showed that the mean AgNOR of acute and chronic aplastic anemia was significantly lower than that of the normal control group. In the acute aplastic anemia, the average value of AgNOR of megakaryocyte, premature neutrophil and early neutrophil decreased significantly (P <0.001 ~ 0.01). There was also a significant difference in mean AgNOR between acute and chronic aplasia (P <0.01). The authors believe that AgNOR technology for pediatric aplastic anemia diagnosis, efficacy determination and explore the mechanism of bone marrow cell dysplasia have some practical value.