EB病毒(EBV)伴随于霍奇金病,但它与患者年龄和组织学分型的关系尚未确定。在霍奇金病的发病机理上受其他淋巴管疱疹病毒,象CMV和人类疱疹病毒6型(HHV-6)侵犯的可能性也不清楚。 研究采用77例霍奇金病的埋植石蜡材料,包括24例儿童标本(平均年龄11.4岁),36例青年标本(平均年龄28.8岁)和17例老年标本(平均年龄53.8岁)。EBV的测定,是在EB编码RNA的基础上,用敏感的点杂交技术在霍奇金-里斯氏细胞 Epstein-Barr virus (EBV) is associated with Hodgkin’s disease but its relationship to patient age and histological type has not been established. The likelihood of other lymphotropic herpesvirus, such as CMV and human herpesvirus 6 (HHV-6), is also not clear in the pathogenesis of Hodgkin’s disease. The study included 77 children with Hodgkin’s disease embedded paraffin, including 24 children (mean age 11.4 years), 36 youth samples (mean age 28.8 years) and 17 elderly patients (mean age 53.8 years). EBV assay is based on the EB-encoding RNA, using a sensitive dot blot technique in Hodgkin-Reesece cells