合并慢性特发性血小板减少性紫癜 (ITP)的心脏病患者 ,接受体外循环 (CPB)心内直视术后 ,会面临较大的出血风险。通过术前应用激素、大剂量静脉注射γ-球蛋白、达那唑 ,术前或同期行脾切除术 ,术中应用膜式氧合器、抑肽酶和 /或止血环酸、肝素涂敷 CPB管道、离心泵、自体血液回收、常温以及 CPB结束后输注血小板等综合措施 ,术后可明显降低此类患者的出血风险。 Cardiac patients with idiopathic thrombocytopenic purpura (ITP) who undergo cardiopulmonary bypass (CPB) undergoing open heart surgery face a greater risk of bleeding. By preoperative application of hormones, high-dose intravenous γ-globulin, danazol, preoperative or concurrent splenectomy, intraoperative application of membrane oxygenator, aprotinin and / or tranexamic acid, heparin coating CPB pipeline, centrifugal pump, self-blood recovery, normal temperature and platelet transfusion after CPB and other comprehensive measures, postoperative can significantly reduce the risk of bleeding in such patients.