补体在机体的免疫系统中起着重要的防御和调节功能,其中以C3尤为重要,因为它是补体活化经典途径和旁路途径的枢纽成份,并通过其活性片段产生多种生物学、免疫学效应,这些效应多是由相应受体介导的。虽然第一个补体受体在30多年前就已发 Complement plays an important defense and regulatory role in the body’s immune system. Of these, C3 is of particular importance because it is the pivotal component of the classical and alternative pathway of complement activation and produces multiple biology through its active fragments, immunology Effect, these effects are mostly mediated by the corresponding receptor. Although the first complement receptor had been made more than 30 years ago