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目的探讨新疆维、汉民族不同年龄段前列腺增生症患者血清PSA、PSAD及前列腺体积的差异及它们之间的相关性。方法总结5年来前列腺增生症住院患者,其中汉族150例,维吾尔族114例,在检查治疗前行放免法检测血清PSA,经腹超声测量前列腺体积,并分别计算患者的PSAD,按照不同年龄段进行血清PSA、PSAD及前列腺体积的比较。结果维、汉民族各年龄段血清PSA及PSAD差异无显著性(P＜0．05)。血清PSA及前列腺体积均随年龄增长而增高,且它们之间关系呈正相关。两民族前列腺体积在60岁组和80岁组差异显著(P＜0．05),维吾尔族明显高于汉族。结论两民族前列腺增生症患者间血清PSA、PSAD差异无显著性,且与前列腺体积一样随年龄增长而增高。PSAD是更可靠的诊断指标。
Objective To investigate the differences of serum PSA, PSAD and prostate volume in patients with benign prostatic hyperplasia at different ages in Xinjiang Uygur and Han ethnic groups and their correlations. Methods A total of 150 hospitalized patients with benign prostatic hyperplasia (BPH) were enrolled in this study. Among them, 150 were Han nationality and 114 were Uygur nationality. Serum PSA was measured by radioimmunoassay before the treatment. Prostate volume was measured by abdominal ultrasonography. PSAD was calculated according to different age groups Serum PSA, PSAD and prostate volume comparison. Results There was no significant difference in serum PSA and PSAD between Han and all ethnic groups (P <0.05). Serum PSA and prostate volume increased with age, and the relationship between them was positively correlated. The two groups of prostate volume in the 60-year-old group and 80-year-old group significant difference (P <0.05), Uighur was significantly higher than Han. Conclusions There is no significant difference in PSA and PSAD between the two groups of patients with benign prostatic hyperplasia, and with the increase of the age, the same as the prostate volume. PSAD is a more reliable diagnostic indicator.