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目的：了解安徽和广州两地农村儿童少年幽门螺杆菌（HP）感染情况。方法：采用血清流行病学方法，对209名20岁以下儿童少年进行HP感染的血清学调查。结果：安徽和广州两地农村HP感染率分别为52．5％和29．6％（P＜0．005）；平均抗体水平分别为1．99±0．42和1．70±0．43（P＜0．005）。父母均为阳性的子女HP感染率为47．8％，平均抗体水平2．10±0．54，明显高于父母均为阴性子女的感染率（24．1％）和平均抗体水平（1．77±0．53）（P＜0．005，P＜0．01）。结论：两地间HP感染率及平均抗体水平有差异。子女HP阳性与父母感染有关。HP可在人与人之间传播。
Objective: To understand the prevalence of Helicobacter pylori (HP) infection among rural children and adolescents in Anhui and Guangzhou. METHODS: Serological epidemiology of 209 HP-infected juveniles under 20 years of age was studied by serological epidemiology. Results: The HP infection rates in rural areas of Anhui and Guangzhou were 52.5% and 29.6%, respectively (P <0.005). The average antibody levels were 1.99 ± 0.42 and 1.70 ± 0.43 (P <0.005). The HP infection rate was 47.8% and the average antibody level was 2.10 ± 0.54, which was significantly higher than that of both parents (24.1%) and the average antibody (1). 77 ± 0.53) (P <0.005, P <0.01). Conclusion: The prevalence of HP infection and the average antibody level between the two places are different. Children HP positive and parental infection. HP can spread from person to person.