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为了探讨慢性细菌性前列腺炎引起不育的机理，本文对１７例经细菌学检查诊断为慢性细菌性前列腺炎（ＣＢＰ）的不育患者和７例正常生育力者进行了研究。包括精液常规检查、ＳＶＴ和精子低渗肿胀试验，精液丙二醛（ＭＤＡ）和精浆ＳＯＤ测定，抗精子抗体与精浆Ｔ细胞ＣＤ４／ＣＤ８比例测定等。结果提示：１．ＣＢＰ可通过多方面机制影响精液质量和男性生育力；２．ＣＢＰ患者精液中白细胞及其活性产物在精子膜过氧化机制中发挥重要作用，并影响精子功能。
In order to investigate the mechanism of infertility caused by chronic bacterial prostatitis, 17 infertile patients diagnosed as chronic bacterial prostatitis (CBP) and 7 normal fertility patients by bacteriological examination were studied in this paper. Including the routine examination of semen, SVT and sperm hypotonic swelling test, semen MDA and seminal plasma SOD determination, anti-sperm antibody and seminal plasma T cells CD4 / CD8 ratio determination. The results suggest: 1. CBP can affect semen quality and male fertility through various mechanisms; 2. Leukocytes and their active products in the seminal fluid of CBP patients play an important role in the mechanism of sperm membrane peroxidation and affect sperm function.