论文部分内容阅读
应用聚合酶链反应（ＰＣＲ）技术，对临床诊断为病毒性心肌炎（４０例）和疑似心肌炎（３０例）的７０例住院病儿进行血清肠道病毒ＲＮＡ检测，其中阳性者４４人，阳性率为６３％，堤示肠道病毒是小儿病毒性心肌炎的主要病原。阳性病人除具有典型的心肌炎症状外，均伴有心电图的异常改变和心肌酶的异常，尤以α－羟丁酸脱氢酶明显增高为特点。本组不但在病程２ｄ至２年的病儿血清中可获阳性结果，而且在临床治愈或好转已２．５个月的病儿血清中仍可检出肠道病毒ＲＮＡ，因而对早期和回顾性诊断都具有较重要的意义，本法具有快速、准确、敏感的特点，具有较高的临床实用性。
Serum enterovirus RNA was detected in 70 hospitalized children with viral myocarditis (40 cases) and suspected myocarditis (30 cases) clinically diagnosed by polymerase chain reaction (PCR) technique, of which 44 were positive, the positive rate 63%, embankment revealed enterovirus is the main pathogen of viral myocarditis in children. In addition to the positive patients with typical symptoms of myocarditis, are associated with abnormal ECG changes and abnormal myocardial enzymes, especially in a-hydroxybutyrate dehydrogenase was significantly increased. This group not only in the duration of 2d to 2 years of sick children serum positive results, and clinical cure or improvement in 2.5 months of sick children can still detect the intestinal virus RNA, so early and review Sexual diagnosis is more important, this method has a fast, accurate and sensitive features, with high clinical practicability.