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目的通过超声造影成像技术的新生血管增强程度评价颈动脉粥样硬化斑块与缺血性脑血管疾病之间的关系。方法将有颈动脉斑块病变的患者分为两组,一组为缺血症状组(63例),另一组为无缺血症状组(27例),对患者颈动脉硬化斑块进行超声造影检查,重点观察颈动脉硬化斑块内新生血管的血流灌注情况,比较有脑缺血症状患者组与无脑缺血症状患者组的颈动脉斑块内新生血管密度及造影增强程度的组间差异。结果有脑缺血症状患者组斑块的造影后增强强度(EI)及ratio值(误差比率值)明显高于无临床症状患者组(P<0.05)。结论超声造影可显示斑块内新生毛细血管的再生情况,可以依据斑块内造影剂增强强度预测缺血性脑血管病发生风险的有效指标。
Objective To evaluate the relationship between carotid atherosclerotic plaques and ischemic cerebrovascular diseases by the degree of neovascularization of ultrasound contrast imaging. Methods Patients with carotid plaque lesions were divided into two groups: one group (63 cases) with ischemic symptoms and the other group (27 cases) without ischemic symptoms. The carotid atherosclerotic plaques Angiography, focus on observation of carotid atherosclerotic plaque neovascularization perfusion, compared with cerebral ischemic symptoms and no ischemic symptoms in patients with carotid plaque neovascularization density and contrast enhancement group Difference between. Results The contrast enhanced intensity (EI) and ratio (error ratio) of plaques in patients with cerebral ischemia were significantly higher than those without clinical symptoms (P <0.05). Conclusion Contrast-enhanced ultrasound can show the regeneration of capillaries in plaque, which can be used to predict the risk of ischemic cerebrovascular disease according to the enhanced intensity of contrast agent in plaque.