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摘要背景非小细胞肺癌(NSCLC)病人的预后很重要,因为可手术切除病灶和有不良预后变量的病人都可能通过新辅助治疗获益。本研究旨在评估SUVmax、SUVmax比值、CT容积(CTvol)、代谢肿瘤体积(MTV)和病灶总糖酵解值(TLG)为生存的预后指标。此外,我们定义了2个变量:MTV乘以SUVmax(MTVmax)和CTvol乘以SUVmax(CTvolmax),并且评估它们是否可以作为预后标志物。方法评估已行手术和18F-FDG PET/CT检查的Ⅰ-Ⅱ期NSCLC病人。采用Cox比例风险模型确定变量和生存期之间的关联。类似的分析在没有淋巴结(LN)转移的病人中进行。结果研究纳入180例病人(研究结
Abstract Background The prognosis of patients with non-small cell lung cancer (NSCLC) is important because neoadjuvant therapy may be of benefit to both surgically-resected lesions and patients with poor prognostic variables. The purpose of this study was to evaluate the prognostic indicators for the survival of SUVmax, SUVmax, CTvol, MTV and TLG. In addition, we define two variables: MTV times SUVmax (MTVmax) and CTvol times SUVmax (CTvolmax), and assess whether they can be used as prognostic markers. Methods Patients with stage I-II NSCLC undergoing surgery and 18F-FDG PET / CT were evaluated. The Cox proportional hazards model was used to determine the association between variables and survival. Similar analyzes were performed in patients without lymph node (LN) metastases. Results The study enrolled 180 patients (Study Results