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目的:探讨正畸治疗中成年女性颊颞部不同区域的软组织变化。方法:选取40位接受正畸治疗的成年女性患者作为实验组，其中拔牙患者20例，非拔牙患者20例；对照组为未接受正畸治疗的成年女性20位。实验组在正畸治疗粘矫治器之前(T0)及正畸治疗开始后5个月(T1)、10个月(T2)、15个月(T3)、20个月(T4)，用3dMDface?扫描仪拍摄面部软组织三维图像。T0-T4平均20.3个月。对照组距首次拍摄后平均17.6个月后再次拍摄面部软组织三维图像。通过Geomagic2013 Wrap对三维图像进行二次处理，重叠T0-T1、T0-T2、T0-T3、T0-T4期图像，比较分析颊颞部不同区域软组织突度变化。结果:成年女性开始正畸治疗5个月后，拔牙组软组织突度变化量颞部-0.46 mm，上颊部内侧区域-0.55 mm，上颊部外侧区域-0.66 mm，下颊部内侧区域-0.97 mm，下颊部外侧区域-1.31 mm。随治疗进展，软组织突度变化量无明显的增加或进一步减小。拔牙与否对颊颞部软组织的减小量无明显影响。17.6个月后未进行正畸治疗的成年女性颊颞部软组织突度几乎没有变化。结论:成年女性正畸治疗过程中，颊颞部各区域软组织变化量随治疗时间推移没有明显变化，拔牙与否及短期内增龄性变化对软组织变化没有明显影响。“,”Objective:This study was performed to investigate facial soft tissue changes in female adultsundergoing orthodontic treatment in thebuccal and temporalregions.Methods:Forty female adultsundergoing orthodontic treatment were selected as the experimental group, including 20 extraction cases and 20 non-extraction cases. The control group consists of 20 adult women without orthodontic treatment.The facial soft tissue was scanned in each patients using the 3 dMDface? scanner before orthodontic treatment (T0), 5 months (T1), 10 months (T2), 15 months (T3) and 20 months (T4) during the treatment. The facial soft tissue of the adult women in the control group wasscanned twice with an average interval of 17.6 months. The T0-T1, T0-T2, T0-T3, and T0-T4 images were superimposed using Geomagic 2013 Wrap to compare the changes of soft tissue depth in the buccal and temporal regions.Results:The soft-tissue draped after 5 months by 0.46 mm intemporal region, 0.55 mm in medial upper buccal region, 0.66 mm in lateral upper buccal region, 0.97 mm in medial lower buccal regionand 1.31 mm inlateral lower buccal region. The soft tissue in upper buccal and temporal region changed in negative direction slightly.Soft tissue in buccal and temporal regionsshowed no difference between extraction and non-extraction groups.Asthe treatment in progress, therewas no significant change in facial soft tissue morphologyafterwards. In the control group, no significant changewas found in thebuccal and temporalregionswithinan average of 17.6 months.Conclusions:No obvious collapse of buccal and temporal softtissue was found in adult patients undergoing orthodontic treatment.Extraction and aging were not the main factors affecting the facial morphology in young adult orthodontic patients.