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磁共振成像(magnetic resonance imaging,MRI)以其非侵入性,无辐射损伤,无骨质伪影,安全性好,空间分辨率和对比度高,可向任意方位断层扫描等技术灵活性,成为了临床医学诊断的重要手段。但是,某些不同组织或肿瘤组织的弛豫时间差别较小,成像时很难获得足够的信号差,造成MRI诊断困难,不能进行动态扫描和测定器官的功能等缺陷,因此需在被检测对象中加入一类能改变氢质子弛豫时间的物质来提高磁共振成像的敏感性和分辨率,这种物质被称为磁共振成像造影剂。临床上50%以上的磁共振扫描需
Magnetic resonance imaging (MRI), with its non-invasive, non-radioactive lesions, boneless artifacts, good safety, high spatial resolution and contrast, and the ability to scan at any orientation, Clinical diagnosis of important means. However, the difference between the relaxation times of some different tissues or tumor tissues is small, it is difficult to obtain sufficient signal difference during imaging, which makes MRI diagnosis difficult, can not perform dynamic scanning and determine the function of organs and other defects. Therefore, Adding a class of substances that change the hydrogen proton relaxation time to improve the sensitivity and resolution of magnetic resonance imaging, a substance known as magnetic resonance imaging contrast agents. More than 50% of clinical MRI scan required