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术前正确估价肝癌患者的肝储备功能已成为肝外科十分重要而又困难的问题。作者分别对不同范围肝切除家兔和肝癌患者手术前后施行胰高血糖素负荷试验（ＧＳＴ），发现ＧＳＴ前后血浆ｃ－ＡＭＰ浓度相差显著，若以负荷前后血浆ｃ－ＡＭＰ的应答比为指标，则ＧＳＴ能较准确地反映肝储备功能，研究结果提示当兔肝切除率在２５％以上时，ＧＳＴ已能检出；并能较好地区分健康人群和肝癌人群的肝功能状态，比常规肝功能试验准确、及时、敏感，具有临床意义。
Preoperative assessment of the hepatic reserve function of liver cancer patients has become a very important and difficult problem in liver surgery. The authors performed a glucagon stress test (GST) before and after surgery in patients with different ranges of hepatectomized rabbits and liver cancer, and found that there was a significant difference in plasma c-AMP concentration before and after GST, if the ratio of plasma c-AMP before and after the load was used as an indicator, The GST can reflect the liver reserve function more accurately. The results suggest that when the rabbit liver resection rate is above 25%, GST can detect; and can better distinguish the liver function status of healthy people and liver cancer population, than the conventional liver Functional tests are accurate, timely and sensitive and have clinical significance.