哌唑嗪(prazosin)为选择性作用于血管神经突触后α_1肾上腺素受体的阻滞剂。临床上主要用于治疗高血压病和慢性充血性心力衰竭。该药用于治疗前列腺增生症,国内报道较少,笔者用哌唑嗪治疗前列腺增生症3例,现报告如下。 例1 男,66yr。1986年4月始感尿频,偶有尿痛,但无血尿。以后逐渐排尿费力,射程缩短,尿线细而无力,排尿次数由每夜1-2次增加到4-5 Prazosin is a selective inhibitor of α 1 adrenergic receptor after vascular synapse. Clinically used mainly for the treatment of hypertension and chronic congestive heart failure. The drug used to treat benign prostatic hyperplasia, less reported in the country, the author with prazosin in the treatment of benign prostatic hyperplasia in 3 cases, are as follows. Example 1 male, 66yr. In April 1986 the beginning of frequent urination, occasional dysuria, but no hematuria. After gradually urination laborious, shorter range, thin and weak urine, urination frequency increased from 1-2 to 4-5 per night