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伊康唑是一种新的三唑类抗真菌剂,在试管内有抗皮肤真菌,念珠菌、隐球菌,瓶形酵母菌和曲菌的作用。它在表浅的和系统性真菌病包括甲真菌中的作用已有证明。作者在一组开放性研究中,对23例皮肤真菌病,指(趾)甲念珠菌感染用伊康唑治疗,观察其疗效及安全度。23例中10例为皮肤真菌病,其中9例鉴定为红色毛癣菌,1例为堇色毛癣菌;余12例为念珠菌感染,1例为短柄帚菌。病期6个月至5年,用真菌病通过直接镜检及培养阳性后确诊。
Iaconazole is a new triazole antifungal agent that has antifungal, Candida, Cryptococcus, bottle yeast and Aspergillus species in test tubes. Its role in superficial and systemic fungal diseases including onychomycosis has been demonstrated. In a panel of open-label studies, 23 patients with dermatophytosis and Candida albicans infection were treated with ibuprofen and observed for efficacy and safety. Of the 23 cases, 10 were dermatophytosis, of which 9 were identified as Trichophyton rubrum and 1 was Trichophyton violaceum; the remaining 12 were Candida infections and one was Pedicularis. Disease period of 6 months to 5 years, with fungal disease by direct microscopy and culture positive after diagnosis.