本文以大鼠为实验动物 ,对四氯化碳、人血白蛋白所致的肝纤维化动物模型 ,与正常大鼠从存活率 ,血清ALT、AST、LDH、肝组织胶原蛋白含量 ,肝脏病理学表现等几个方面进行了比较 ,各项测试指标与正常大鼠比较差异极为显著 ,均能反映出肝纤维化的形成 ,各项测试指标可作为实验性肝纤维化治疗研究的参考指标 In this paper, the rats as experimental animals, carbon tetrachloride, human serum albumin-induced liver fibrosis animal model, and normal rats from the survival rate, serum ALT, AST, LDH, liver tissue collagen content, liver disease Physical performance and other aspects were compared, the test indicators and normal rats were extremely significant differences, can reflect the formation of liver fibrosis, the test indicators can be used as a reference for the experimental treatment of liver fibrosis