本文总结1996年10月至1999年12月25例凝血酶胸腔内注入治疗自发性气胸临床资料,现报告如下。1 临床资料 25例发病年龄20～25岁,男:女比例为6.6:1。所有病例均符合自发性气胸诊断标准。特发性气胸10例,自发性气胸15例。25例均为中等量以上气胸,其中复发性气胸10例。入院后立即予以常规闭式引流术,并使用抗生素、解痉平喘等药物治疗。结合临床症状、体征、辅助检查等提示肺组织完全复张后,全部病例从引流管向胸腔内注入凝血酶400U、利多卡因50mg、0.9％NS20ml,边注药边让病人变动体位,嘱其头低侧卧位1～6h,每半小时翻身1次,定时观察水封瓶水柱波动情况。结果:特发性气胸有效率100％,继发性气胸有效率73％,总有效率84％。2 讨论 This article summarizes from October 1996 to December 1999 25 cases of thrombin thoracic injection of the treatment of spontaneous pneumothorax clinical data are as follows. 1 clinical data 25 cases of age 20 to 25 years old, male: female ratio of 6.6: 1. All cases were consistent with spontaneous pneumothorax diagnostic criteria. 10 cases of idiopathic pneumothorax, 15 cases of spontaneous pneumothorax. 25 cases were moderate amount of pneumothorax, of which 10 cases of recurrent pneumothorax. Immediately after admission to conventional closed drainage, and the use of antibiotics, antispasmodic asthma and other drug treatment. Combined with clinical symptoms, signs, laboratory tests, etc. prompted complete recovery of lung tissue, all patients from the drainage tube to the thoracic cavity into the thrombin 400U, lidocaine 50mg, 0.9% NS20ml side injection while allowing patients to change position, Head low side position 1 ~ 6h, stand up every half an hour, regular observation of water seal water bottle fluctuations. Results: The effective rate of idiopathic pneumothorax was 100%, the effective rate of secondary pneumothorax was 73% and the total effective rate was 84%. 2 discussions