日本Akita红十字医院等1994年5月至1995年4月间收集了112例结直肠癌,其中粘膜下侵入(sm)癌32例、进展癌80例。以结肠镜检在肿瘤周围是否伴有白斑分为两组,对每一例均检查了淋巴结和肝转移。在sm癌中,两组的转移情况没有差别,但进展癌中淋巴结转移在两组中具显著差异(P<0.05),肝转移则无差别。免疫细胞化学法观察切片见大量T细 In Akika Red Cross Hospital in Japan, between May 1994 and April 1995, 112 cases of colorectal cancer were collected, including 32 cases of submucosal invasion (sm) and 80 cases of advanced cancer. The presence of leukoplakia around the tumor with colonoscopy was divided into two groups, lymph node and liver metastases were examined for each case. In sm cancer, there was no difference in metastasis between the two groups, but lymph node metastasis in advanced cancer was significantly different between the two groups (P<0.05). There was no difference in liver metastasis. Immunocytochemical observation of a large number of fine T