自主细小病毒宿主广泛,对肿瘤细胞和转化细胞有选择性杀伤,具有亲瘤性和溶瘤性,迄今未发现对人类有致病性,非常有希望成为一个新的抗肿瘤制剂。全文综述细小病毒的结构和功能、抗肿瘤作用及机制、易感性、致病性等方面的研究进展。 A wide range of autonomous parvovirus host, selective killing of tumor cells and transformed cells, with oncolytic and oncolytic, so far no human pathogenic, very promising to become a new antitumor agent. The article reviews the research progress of the structure and function of parvovirus, antitumor effect and mechanism, susceptibility and pathogenicity.