目的研制积雪苷口腔崩解片。方法以积雪苷为主药,内加淀粉为崩解剂,建立性状、崩解时限、含量测定等质控方法。结果制备的口腔崩解片符合工艺要求。以高效液相色谱法测定积雪苷口腔崩解片中积雪草苷的含量,平均回收率为100.7%,RSD=1.01%(n=9)。结论该制剂制备工艺可行,测定方法简便、准确。 Objective To develop oral glucocorticoid tablets. Methods With asiaticoside as the main drug and starch as disintegrating agent, quality control methods such as traits, disintegration time and content determination were established. Results prepared orally disintegrating tablets meet the technical requirements. The content of asiaticoside in asiatic orally disintegrating tablets was determined by HPLC. The average recovery was 100.7% with RSD = 1.01% (n = 9). Conclusion The preparation process is feasible, the determination method is simple and accurate.